7A3Q

Crystal structure of dengue 4 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Envelope protein E	polymer	395	43335.5	2	UniProt (S5S2D1) Pfam (PF00869) Pfam (PF02832) UniProt (by SIFTS) (P09866)	Dengue virus 4	Matrix protein,Small envelope protein M
2	C, D (H, I)	Single Chain Variable Fragment	polymer	144	15679.2	2		Homo sapiens (Human)
3	E, F (L, M)	Single Chain Variable Fragment	polymer	154	15632.8	2		Homo sapiens (Human)
4	G, H (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	I, J (H, I)	(2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid	non-polymer		237.3	2	Chemie (3CX)
6	K, L, M, N, O (A, B, H, I, L)	water	water		18.0	40	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	149294.9
Non-Polymers*	Number of molecules	4
	Total formula weight	917.0
All*	Total formula weight	150212.0

*Water molecules are not included.