7A20
Azobenzene-Based Inhibitors for Tryptophan Synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tryptophan synthase alpha chain,Tryptophan synthase beta chain | polymer | 709 | 76456.1 | 4 | UniProt (A0A0D6FWC1) UniProt (A0A0F7J6T4) Pfam (PF00290) Pfam (PF00291) UniProt (by SIFTS) (P00929) UniProt (by SIFTS) (P0A2K1) | Salmonella typhimurium | |
| 2 | E, G (B, D) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | F, H (B, D) | TRIS-HYDROXYMETHYL-METHYL-AMMONIUM | non-polymer | 122.1 | 2 | Chemie (144) | |||
| 4 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 268 (UniProt: A0A0D6FWC1)
A, B, C, D: 278 - 670 (UniProt: A0A0F7J6T4)
| PDB | External Database | Details |
|---|---|---|
| Ser -25 | - | expression tag |
| Thr -24 | - | expression tag |
| Thr -23 | - | expression tag |
| Arg -22 | - | expression tag |
| Pro -21 | - | expression tag |
| Ala -20 | - | expression tag |
| Met -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 269 | - | linker |
| Thr 270 | - | linker |
| Thr 271 | - | linker |
| Arg 272 | - | linker |
| Pro 273 | - | linker |
| Met 274 | - | linker |
| Thr 275 | - | linker |
| Thr 276 | - | linker |
| Leu 277 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Lys 671 | - | expression tag |
| Leu 672 | - | expression tag |
| Ala 673 | - | expression tag |
| Ala 674 | - | expression tag |
| Ala 675 | - | expression tag |
| Leu 676 | - | expression tag |
| Glu 677 | - | expression tag |
| His 678 | - | expression tag |
| His 679 | - | expression tag |
| His 680 | - | expression tag |
| His 681 | - | expression tag |
| His 682 | - | expression tag |
| His 683 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 305824.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 290.3 | |
| All* | Total formula weight | 306114.6 |
