7A1Y
KRASG12C GDP form in complex with Cpd2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | GTPase KRas | polymer | 170 | 19374.9 | 1 | UniProt (P01116) Pfam (PF00071) In PDB | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
2 | A | ~{N}-(3-bromanyl-2,6-dimethyl-pyridin-4-yl)propanamide | non-polymer | 257.1 | 1 | Chemie (QWH) | |||
3 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
6 | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 1 - 164 (UniProt: P01116)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Cys 12 | Gly 12 | engineered mutation |
Gly 151 | Arg 151 | conflict |
Asp 153 | Glu 153 | conflict |
Lys 165 | - | expression tag |
His 166 | - | expression tag |
Lys 167 | - | expression tag |
Glu 168 | - | expression tag |
Lys 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19374.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 820.7 | |
All* | Total formula weight | 20195.6 |