7A1S
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 3-methyl-2-oxoglutarate, AND TANKYRASE-2 (TNKS2) FRAGMENT PEPTIDE (21-MER)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 349 | 40328.3 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (Human) | Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase |
2 | B (B) | TANKYRASE-2 | polymer | 20 | 2229.4 | 1 | UniProt (by SIFTS) (Q9H2K2) | Homo sapiens | |
3 | C, D, E, F, G... (A) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
4 | K (A) | (3~{S})-3-methyl-2-oxidanylidene-pentanedioic acid | non-polymer | 160.1 | 1 | Chemie (ROQ) | |||
5 | L (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
6 | M, N (A, B) | water | water | 18.0 | 307 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 42557.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 994.0 | |
All* | Total formula weight | 43551.7 |