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7A1S

FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 3-methyl-2-oxoglutarate, AND TANKYRASE-2 (TNKS2) FRAGMENT PEPTIDE (21-MER)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hypoxia-inducible factor 1-alpha inhibitorpolymer34940328.31UniProt (Q9NWT6)
Pfam (PF13621)
Homo sapiens (Human)Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase
2B
(B)
TANKYRASE-2polymer202229.41UniProt (by SIFTS) (Q9H2K2)Homo sapiens
3C, D, E, F, G...
(A)
SULFATE IONnon-polymer96.18Chemie (SO4)
4K
(A)
(3~{S})-3-methyl-2-oxidanylidene-pentanedioic acidnon-polymer160.11Chemie (ROQ)
5L
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
6M, N
(A, B)
waterwater18.0307Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42557.7
Non-Polymers*Number of molecules10
Total formula weight994.0
All*Total formula weight43551.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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