6ZX3
OMPD-domain of human UMPS in complex with 6-thiocarboxamido-UMP at 1.15 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Uridine 5'-monophosphate synthase | polymer | 260 | 28299.7 | 1 | UniProt (P11172) Pfam (PF00215) | Homo sapiens (Human) | UMP synthase |
| 2 | B (A) | [(2~{R},3~{S},4~{R},5~{R})-5-[6-carbamothioyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate | non-polymer | 383.3 | 1 | Chemie (QRZ) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) | |||
| 5 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | F (A) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A: 224 - 480 (UniProt: P11172)
| PDB | External Database | Details |
|---|---|---|
| Gly 221 | - | expression tag |
| Ala 222 | - | expression tag |
| Met 223 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28299.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 686.6 | |
| All* | Total formula weight | 28986.3 |
