6ZVP
Atomic model of the EM-based structure of the full-length tyrosine hydroxylase in complex with dopamine (residues 40-497) in which the regulatory domain (residues 40-165) has been included only with the backbone atoms
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (D, A, B, C) | Tyrosine 3-monooxygenase | polymer | 458 | 51399.9 | 4 | UniProt (P07101) Pfam (PF12549) Pfam (PF21417) Pfam (PF00351) | Homo sapiens (Human) | Tyrosine 3-hydroxylase,TH |
| 2 | E, G, I, K (D, A, B, C) | FE (III) ION | non-polymer | 55.8 | 4 | Chemie (FE) | |||
| 3 | F, H, J, L (D, A, B, C) | L-DOPAMINE | non-polymer | 153.2 | 4 | Chemie (LDP) |
Sequence modifications
D, A, B, C: 40 - 497 (UniProt: P07101)
| PDB | External Database | Details |
|---|---|---|
| Met 81 | Val 112 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 205599.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 836.1 | |
| All* | Total formula weight | 206435.5 |
