6ZSJ
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ras-related protein Rab-8A | polymer | 178 | 20476.6 | 2 | UniProt (P61006) Pfam (PF00071) | Homo sapiens (Human) | Oncogene c-mel |
| 2 | C, D (C, D) | EH domain-binding protein 1 | polymer | 156 | 18578.0 | 2 | UniProt (Q8NDI1) Pfam (PF12130) | Homo sapiens (Human) | |
| 3 | E, G (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 4 | F, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 176 (UniProt: P61006)
C, D: 1060 - 1212 (UniProt: Q8NDI1)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 1057 | - | expression tag |
| His 1058 | - | expression tag |
| Met 1059 | - | expression tag |
| Ala 1120 | Phe 1120 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 78109.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1093.0 | |
| All* | Total formula weight | 79202.2 |
