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6ZS5

3.5 A cryo-EM structure of human uromodulin filament core

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, D)
Uromodulinpolymer64069821.72UniProt (P07911)
Pfam (PF12947)
Pfam (PF07645)
Pfam (PF23283)
Pfam (PF23344)
Pfam (PF00100)
Homo sapiens (Human)Tamm-Horsfall urinary glycoprotein,THP
2C
(B)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G22768VO)
3D
(C)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight139643.4
BranchedNumber of molecules2
Total formula weight1335.2
All*Total formula weight140978.6
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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