6ZRH
Crystal structure of OXA-10loop24 in complex with ertapenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-lactamase | polymer | 243 | 27377.2 | 4 | UniProt (Q7BNC2) Pfam (PF00905) | Escherichia coli | |
| 2 | E, G, J, Q (A, B, C, D) | (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid | non-polymer | 477.5 | 4 | Chemie (2RG) | |||
| 3 | F, H, I, K, L... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 14 | Chemie (EDO) | |||
| 4 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 1071 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 263 (UniProt: Q7BNC2)
| PDB | External Database | Details |
|---|---|---|
| Trp 208 | Phe 208 | conflict |
| - | Ser 209 | deletion |
| Met 210 | Val 211 | conflict |
| Val 212 | Thr 213 | conflict |
| - | Glu 214 | deletion |
| - | Ser 215 | deletion |
| Thr 213 | Asn 216 | conflict |
| Gln 215 | Gly 218 | conflict |
| Gly 217 | Ala 220 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 109508.8 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2779.1 | |
| All* | Total formula weight | 112287.9 |
