6ZRH

Crystal structure of OXA-10loop24 in complex with ertapenem

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008658	molecular_function	penicillin binding
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding
A	0071555	biological_process	cell wall organization
B	0008658	molecular_function	penicillin binding
B	0008800	molecular_function	beta-lactamase activity
B	0016787	molecular_function	hydrolase activity
B	0017001	biological_process	antibiotic catabolic process
B	0046677	biological_process	response to antibiotic
B	0046872	molecular_function	metal ion binding
B	0071555	biological_process	cell wall organization
C	0008658	molecular_function	penicillin binding
C	0008800	molecular_function	beta-lactamase activity
C	0016787	molecular_function	hydrolase activity
C	0017001	biological_process	antibiotic catabolic process
C	0046677	biological_process	response to antibiotic
C	0046872	molecular_function	metal ion binding
C	0071555	biological_process	cell wall organization
D	0008658	molecular_function	penicillin binding
D	0008800	molecular_function	beta-lactamase activity
D	0016787	molecular_function	hydrolase activity
D	0017001	biological_process	antibiotic catabolic process
D	0046677	biological_process	response to antibiotic
D	0046872	molecular_function	metal ion binding
D	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue 2RG A 301

Chain	Residue
A	ALA66
A	HOH536
A	SER67
A	SER115
A	VAL117
A	LEU155
A	THR206
A	GLY207
A	TRP208
A	ARG247

---

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 302

Chain	Residue
A	ASN85
A	HIS87
A	HOH405
D	LEU175
D	ASN176
D	LYS182

---

site_id	AC3
Number of Residues	8
Details	binding site for residue EDO B 302

Chain	Residue
B	GLN113
B	THR194
B	SER204
B	LYS205
B	THR206
B	HOH412
B	HOH435
B	HOH466

---

site_id	AC4
Number of Residues	4
Details	binding site for residue EDO B 303

Chain	Residue
B	VAL89
B	ASP105
B	HOH516
C	THR227

---

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO C 302

Chain	Residue
B	LEU186
B	LYS189
B	GLU190
C	GLU86
C	GLU190
C	HOH513

---

site_id	AC6
Number of Residues	5
Details	binding site for residue EDO C 303

Chain	Residue
B	GLU224
B	GLU226
B	HOH482
C	THR107
C	ARG109

---

site_id	AC7
Number of Residues	8
Details	binding site for residue EDO C 304

Chain	Residue
C	GLU195
C	TYR200
C	VAL202
C	TRP219
C	THR252
C	ILE261
C	HOH516
C	HOH594

---

site_id	AC8
Number of Residues	6
Details	binding site for residue EDO C 305

Chain	Residue
C	GLU126
D	GLU256
D	GLY259
D	ILE261
D	GLY262
D	HOH510

---

site_id	AC9
Number of Residues	7
Details	binding site for residue EDO C 306

Chain	Residue
B	THR107
B	ARG109
C	GLU199
C	GLU224
C	GLU226
C	HOH502
C	HOH566

---

site_id	AD1
Number of Residues	7
Details	binding site for residue EDO C 307

Chain	Residue
C	ALA36
C	ASN38
C	HOH411
D	ARG58
D	LYS61
D	HOH409
D	HOH537

---

site_id	AD2
Number of Residues	7
Details	binding site for residue EDO D 302

Chain	Residue
A	THR107
A	ARG109
D	GLU199
D	GLU224
D	GLU226
D	HOH468
D	HOH503

---

site_id	AD3
Number of Residues	4
Details	binding site for residue EDO D 303

Chain	Residue
A	HOH499
D	THR107
D	ARG109
D	EDO306

---

site_id	AD4
Number of Residues	3
Details	binding site for residue EDO D 304

Chain	Residue
D	GLY149
D	ILE150
D	HOH512

---

site_id	AD5
Number of Residues	5
Details	binding site for residue EDO D 305

Chain	Residue
D	ARG131
D	TYR135
D	HOH509
D	HOH555
D	HOH562

---

site_id	AD6
Number of Residues	7
Details	binding site for residue EDO D 306

Chain	Residue
A	PRO198
A	HOH412
D	ARG104
D	GLY110
D	2RG301
D	EDO303
D	HOH558

---

site_id	AD7
Number of Residues	15
Details	binding site for Di-peptide 2RG B 301 and SER B 67

Chain	Residue
B	SER115
B	VAL117
B	LEU155
B	LYS205
B	THR206
B	GLY207
B	TRP208
B	ARG247
B	HOH559
B	PRO65
B	ALA66
B	THR68
B	PHE69
B	KCX70
B	GLN101

---

site_id	AD8
Number of Residues	20
Details	binding site for Di-peptide 2RG C 301 and SER C 67

Chain	Residue
B	PRO198
C	PRO65
C	ALA66
C	THR68
C	PHE69
C	KCX70
C	MET99
C	GLN101
C	ARG104
C	VAL114
C	SER115
C	VAL117
C	LEU155
C	LYS205
C	THR206
C	GLY207
C	TRP208
C	ARG247
C	HOH418
C	HOH583

---

site_id	AD9
Number of Residues	20
Details	binding site for Di-peptide 2RG D 301 and SER D 67

Chain	Residue
A	PRO198
D	PRO65
D	ALA66
D	THR68
D	PHE69
D	KCX70
D	MET99
D	GLN101
D	ARG104
D	VAL114
D	SER115
D	VAL117
D	LEU155
D	LYS205
D	THR206
D	GLY207
D	TRP208
D	ARG247
D	EDO306
D	HOH402

---

Functional Information from PROSITE/UniProt

site_id	PS00337
Number of Residues	11
Details	BETA_LACTAMASE_D Beta-lactamase class-D active site. PaSTFKIPnAI

Chain	Residue	Details
A	PRO65-ILE75

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