6ZR6
17beta-hydroxysteroid dehydrogenase type 14 variant S205 in complex with non-steroidal inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 17-beta-hydroxysteroid dehydrogenase 14 | polymer | 270 | 28329.4 | 1 | UniProt (Q9BPX1) Pfam (PF13561) In PDB | Homo sapiens (Human) | 17-beta-HSD 14,17-beta-hydroxysteroid dehydrogenase DHRS10,Dehydrogenase/reductase SDR family member 10,Retinal short-chain dehydrogenase/reductase retSDR3,Short chain dehydrogenase/reductase family 47C member 1 |
| 2 | A | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) | |||
| 3 | A | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | A | [6-(3,4-dihydroxyphenyl)pyridin-2-yl](4-fluoro-3-hydroxyphenyl)methanone | non-polymer | 325.3 | 1 | Chemie (F45) | |||
| 6 | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A: 1 - 270 (UniProt: Q9BPX1)
| PDB | External Database | Details |
|---|---|---|
| Ser 205 | Thr 205 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28329.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1191.9 | |
| All* | Total formula weight | 29521.3 |
