6ZR5
Crystal structure of JNK1 in complex with ATF2(19-58)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Mitogen-activated protein kinase 8 | polymer | 366 | 42032.6 | 2 | UniProt (P45983) Pfam (PF00069) | Homo sapiens (Human) | MAPK 8,JNK-46,Stress-activated protein kinase 1c,SAPK1c,Stress-activated protein kinase JNK1,c-Jun N-terminal kinase 1 |
| 2 | B, D (C, D) | Cyclic AMP-dependent transcription factor ATF-2 | polymer | 40 | 4585.3 | 2 | UniProt (P15336) | Homo sapiens (Human) | cAMP-dependent transcription factor ATF-2,Activating transcription factor 2,Cyclic AMP-responsive element-binding protein 2,cAMP-responsive element-binding protein 2,HB16,Histone acetyltransferase ATF2,cAMP response element-binding protein CRE-BP1 |
| 3 | E, G, J, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | F, I (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 5 | H, L (C, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | M, N, O, P (A, C, B, D) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 364 (UniProt: P45983)
C, D: 20 - 58 (UniProt: P15336)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Tyr 19 | - | expression tag |
| Arg 34 | Gln 34 | engineered mutation |
| Arg 47 | His 47 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93235.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1240.4 | |
| All* | Total formula weight | 94476.1 |
