6ZOY
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1247 | 138282.9 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 2 | D, E, F, G, H... (D, E, F, G, H...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 3 | AA, BA, CA, DA, EA... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 36 | Chemie (NAG) |
Sequence modifications
A, B, C: 14 - 1211 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Glu 10 | - | expression tag |
| Thr 11 | - | expression tag |
| Gly 12 | - | expression tag |
| Thr 13 | - | expression tag |
| Cys 383 | Ser 383 | engineered mutation |
| - | Pro 681 | deletion |
| - | Arg 682 | deletion |
| - | Arg 683 | deletion |
| - | Ala 684 | deletion |
| Cys 985 | Asp 985 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
| Gly 1212 | - | expression tag |
| Ser 1213 | - | expression tag |
| Gly 1214 | - | expression tag |
| Arg 1215 | - | expression tag |
| Glu 1216 | - | expression tag |
| Asn 1217 | - | expression tag |
| Leu 1218 | - | expression tag |
| Tyr 1219 | - | expression tag |
| Phe 1220 | - | expression tag |
| Gln 1221 | - | expression tag |
| Gly 1222 | - | expression tag |
| Gly 1223 | - | expression tag |
| Gly 1224 | - | expression tag |
| Gly 1225 | - | expression tag |
| Ser 1226 | - | expression tag |
| Gly 1227 | - | expression tag |
| Tyr 1228 | - | expression tag |
| Ile 1229 | - | expression tag |
| Pro 1230 | - | expression tag |
| Glu 1231 | - | expression tag |
| Ala 1232 | - | expression tag |
| Pro 1233 | - | expression tag |
| Arg 1234 | - | expression tag |
| Asp 1235 | - | expression tag |
| Gly 1236 | - | expression tag |
| Gln 1237 | - | expression tag |
| Ala 1238 | - | expression tag |
| Tyr 1239 | - | expression tag |
| Val 1240 | - | expression tag |
| Arg 1241 | - | expression tag |
| Lys 1242 | - | expression tag |
| Asp 1243 | - | expression tag |
| Gly 1244 | - | expression tag |
| Glu 1245 | - | expression tag |
| Trp 1246 | - | expression tag |
| Val 1247 | - | expression tag |
| Leu 1248 | - | expression tag |
| Leu 1249 | - | expression tag |
| Ser 1250 | - | expression tag |
| Thr 1251 | - | expression tag |
| Phe 1252 | - | expression tag |
| Leu 1253 | - | expression tag |
| Gly 1254 | - | expression tag |
| His 1255 | - | expression tag |
| His 1256 | - | expression tag |
| His 1257 | - | expression tag |
| His 1258 | - | expression tag |
| His 1259 | - | expression tag |
| His 1260 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 414848.8 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 5092.8 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 7963.5 | |
| All* | Total formula weight | 427905.1 |
