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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6ZN5

SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1B40S ribosomal protein SApolymer20623102.61UniProt (P08865)
Pfam (PF00318)
In PDB		Homo sapiens (Human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
2C40S ribosomal protein S3apolymer21324759.11UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
3D40S ribosomal protein S2polymer21824091.51UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Homo sapiens (Human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
4E40S ribosomal protein S4, X isoformpolymer26229523.71UniProt (P62701)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Homo sapiens (Human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
5F40S ribosomal protein S3polymer22524970.31UniProt (P23396)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS3
6G40S ribosomal protein S6polymer23026599.51UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (Human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
7H40S ribosomal protein S7polymer18621315.91UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS7
8I40S ribosomal protein S8polymer20523946.01UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS8
9J40S ribosomal protein S9polymer18021279.31UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS4
10K40S ribosomal protein S5polymer18921327.71UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS7
11L40S ribosomal protein S11polymer15117528.71UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS17
12M40S ribosomal protein S10polymer9511372.41UniProt (P46783)
Pfam (PF03501)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS10
13N40S ribosomal protein S13polymer14917057.11UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS15
14O40S ribosomal protein S12polymer12313709.11UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS12
15P40S ribosomal protein S14polymer13514457.61UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS11
16Q40S ribosomal protein S15polymer12014067.61UniProt (P62841)
Pfam (PF00203)
In PDB		Homo sapiens (Human)RIG protein,Small ribosomal subunit protein uS19
17R40S ribosomal protein S16polymer13915765.51UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS9
18S40S ribosomal protein S17polymer13215250.71UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS17
19T40S ribosomal protein S18polymer14316811.61UniProt (P62269)
Pfam (PF00416)
In PDB		Homo sapiens (Human)Ke-3,Ke3,Small ribosomal subunit protein uS13
20U40S ribosomal protein S19polymer14415960.41UniProt (P39019)
Pfam (PF01090)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS19
21V40S ribosomal protein S20polymer10111508.61UniProt (P60866)
Pfam (PF00338)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS10
22W40S ribosomal protein S15apolymer12914734.41UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS8
23X40S ribosomal protein S23polymer14115626.41UniProt (P62266)
Pfam (PF00164)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS12
24Y40S ribosomal protein S24polymer12414476.11UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS24
25Z40S ribosomal protein S21polymer828977.21UniProt (P63220)
Pfam (PF01249)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS21
26a40S ribosomal protein S25polymer728182.71UniProt (P62851)
Pfam (PF03297)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS25
27b40S ribosomal protein S27polymer829210.81UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (Human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
28c40S ribosomal protein S26polymer10111645.81UniProt (P62854)
Pfam (PF01283)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS26
29d40S ribosomal protein S28polymer616878.91UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS28
30e40S ribosomal protein S30polymer566302.51UniProt (P62861)
Pfam (PF04758)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS30
31f40S ribosomal protein S29polymer546502.61UniProt (P62273)
Pfam (PF00253)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS14
32gRibosomal protein S27apolymer728453.11UniProt (Q5RKT7)
Pfam (PF01599)
UniProt (by SIFTS) (P62979)
In PDB		Homo sapiens (Human)
33jReceptor of activated protein C kinase 1polymer31434726.21UniProt (P63244)
Pfam (PF00400)
In PDB		Homo sapiens (Human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1
34218S ribosomal RNApolymer1868602432.61GenBank (337376)Homo sapiens (Human)
35iNon-structural protein 1polymer18019801.31UniProt (P0DTD1)
Pfam (PF11501)
In PDB		Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)pp1ab,ORF1ab polyprotein,Non-structural protein 1
36uPre-rRNA-processing protein TSR1 homologpolymer80491951.21UniProt (Q2NL82)
Pfam (PF22298)
Pfam (PF08142)
Pfam (PF04950)
In PDB		Homo sapiens (Human)
37c, f, gZINC IONnon-polymer65.43Chemie (ZN)
Sequence modifications
2: 1 - 1869 (GenBank: 337376)
PDBExternal DatabaseDetails
C 1772G 1872conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains36
Total formula weight1264306.5
Non-Polymers*Number of molecules3
Total formula weight196.2
All*Total formula weight1264502.7
*Water molecules are not included.

224004

PDB entries from 2024-08-21

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