6ZN5

SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2

Functional Information from GO Data

Chain	GOid	namespace	contents
b	0002181	biological_process	cytoplasmic translation
b	0003677	molecular_function	DNA binding
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005730	cellular_component	nucleolus
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006364	biological_process	rRNA processing
b	0006412	biological_process	translation
b	0008270	molecular_function	zinc ion binding
b	0014069	cellular_component	postsynaptic density
b	0022626	cellular_component	cytosolic ribosome
b	0022627	cellular_component	cytosolic small ribosomal subunit
b	0032040	cellular_component	small-subunit processome
b	0042274	biological_process	ribosomal small subunit biogenesis
B	0003735	molecular_function	structural constituent of ribosome
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0015935	cellular_component	small ribosomal subunit
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
e	0003735	molecular_function	structural constituent of ribosome
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005654	cellular_component	nucleoplasm
E	0005730	cellular_component	nucleolus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0005925	cellular_component	focal adhesion
E	0006412	biological_process	translation
E	0008284	biological_process	positive regulation of cell population proliferation
E	0015935	cellular_component	small ribosomal subunit
E	0016020	cellular_component	membrane
E	0022626	cellular_component	cytosolic ribosome
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	0032040	cellular_component	small-subunit processome
E	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
E	0042274	biological_process	ribosomal small subunit biogenesis
E	0045202	cellular_component	synapse
E	0045727	biological_process	positive regulation of translation
E	0070062	cellular_component	extracellular exosome
E	1990904	cellular_component	ribonucleoprotein complex
f	0002181	biological_process	cytoplasmic translation
f	0003735	molecular_function	structural constituent of ribosome
f	0005654	cellular_component	nucleoplasm
f	0005737	cellular_component	cytoplasm
f	0005783	cellular_component	endoplasmic reticulum
f	0005791	cellular_component	rough endoplasmic reticulum
f	0005829	cellular_component	cytosol
f	0005840	cellular_component	ribosome
f	0005925	cellular_component	focal adhesion
f	0006412	biological_process	translation
f	0008270	molecular_function	zinc ion binding
f	0015935	cellular_component	small ribosomal subunit
f	0022626	cellular_component	cytosolic ribosome
f	0022627	cellular_component	cytosolic small ribosomal subunit
f	0070062	cellular_component	extracellular exosome
f	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
F	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
F	0002181	biological_process	cytoplasmic translation
F	0002183	biological_process	cytoplasmic translational initiation
F	0003677	molecular_function	DNA binding
F	0003684	molecular_function	damaged DNA binding
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
F	0004520	molecular_function	DNA endonuclease activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005743	cellular_component	mitochondrial inner membrane
F	0005759	cellular_component	mitochondrial matrix
F	0005783	cellular_component	endoplasmic reticulum
F	0005819	cellular_component	spindle
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0005886	cellular_component	plasma membrane
F	0005925	cellular_component	focal adhesion
F	0006281	biological_process	DNA repair
F	0006284	biological_process	base-excision repair
F	0006412	biological_process	translation
F	0006974	biological_process	DNA damage response
F	0007059	biological_process	chromosome segregation
F	0008017	molecular_function	microtubule binding
F	0010628	biological_process	positive regulation of gene expression
F	0014069	cellular_component	postsynaptic density
F	0015631	molecular_function	tubulin binding
F	0015935	cellular_component	small ribosomal subunit
F	0016020	cellular_component	membrane
F	0017148	biological_process	negative regulation of translation
F	0019104	molecular_function	DNA N-glycosylase activity
F	0019899	molecular_function	enzyme binding
F	0019900	molecular_function	kinase binding
F	0019901	molecular_function	protein kinase binding
F	0022626	cellular_component	cytosolic ribosome
F	0022627	cellular_component	cytosolic small ribosomal subunit
F	0030544	molecular_function	Hsp70 protein binding
F	0031116	biological_process	positive regulation of microtubule polymerization
F	0031397	biological_process	negative regulation of protein ubiquitination
F	0032357	molecular_function	oxidized purine DNA binding
F	0032358	molecular_function	oxidized pyrimidine DNA binding
F	0032587	cellular_component	ruffle membrane
F	0034614	biological_process	cellular response to reactive oxygen species
F	0042981	biological_process	regulation of apoptotic process
F	0044390	molecular_function	ubiquitin-like protein conjugating enzyme binding
F	0045202	cellular_component	synapse
F	0045738	biological_process	negative regulation of DNA repair
F	0045739	biological_process	positive regulation of DNA repair
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0051018	molecular_function	protein kinase A binding
F	0051225	biological_process	spindle assembly
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051879	molecular_function	Hsp90 protein binding
F	0061481	biological_process	response to TNF agonist
F	0070062	cellular_component	extracellular exosome
F	0070181	molecular_function	small ribosomal subunit rRNA binding
F	0070301	biological_process	cellular response to hydrogen peroxide
F	0071159	cellular_component	NF-kappaB complex
F	0072686	cellular_component	mitotic spindle
F	0097100	molecular_function	supercoiled DNA binding
F	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F	0140297	molecular_function	DNA-binding transcription factor binding
F	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
F	1902231	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
F	1905053	biological_process	positive regulation of base-excision repair
F	1990904	cellular_component	ribonucleoprotein complex
F	2000144	biological_process	positive regulation of DNA-templated transcription initiation
F	2001235	biological_process	positive regulation of apoptotic signaling pathway
g	0003735	molecular_function	structural constituent of ribosome
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005783	cellular_component	endoplasmic reticulum
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0006364	biological_process	rRNA processing
G	0006412	biological_process	translation
G	0008284	biological_process	positive regulation of cell population proliferation
G	0015935	cellular_component	small ribosomal subunit
G	0016020	cellular_component	membrane
G	0019901	molecular_function	protein kinase binding
G	0022626	cellular_component	cytosolic ribosome
G	0022627	cellular_component	cytosolic small ribosomal subunit
G	0030425	cellular_component	dendrite
G	0031929	biological_process	TOR signaling
G	0032040	cellular_component	small-subunit processome
G	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
G	0042274	biological_process	ribosomal small subunit biogenesis
G	0042593	biological_process	glucose homeostasis
G	0043065	biological_process	positive regulation of apoptotic process
G	0044297	cellular_component	cell body
G	1990904	cellular_component	ribonucleoprotein complex
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003730	molecular_function	mRNA 3'-UTR binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005730	cellular_component	nucleolus
H	0005737	cellular_component	cytoplasm
H	0005813	cellular_component	centrosome
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0005925	cellular_component	focal adhesion
H	0006364	biological_process	rRNA processing
H	0006412	biological_process	translation
H	0016020	cellular_component	membrane
H	0019901	molecular_function	protein kinase binding
H	0022626	cellular_component	cytosolic ribosome
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	0032040	cellular_component	small-subunit processome
H	0032991	cellular_component	protein-containing complex
H	0042274	biological_process	ribosomal small subunit biogenesis
H	0045202	cellular_component	synapse
H	0048027	molecular_function	mRNA 5'-UTR binding
H	1902255	biological_process	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
H	1990904	cellular_component	ribonucleoprotein complex
H	1990948	molecular_function	ubiquitin ligase inhibitor activity
H	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005730	cellular_component	nucleolus
I	0005737	cellular_component	cytoplasm
I	0005783	cellular_component	endoplasmic reticulum
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0005925	cellular_component	focal adhesion
I	0006412	biological_process	translation
I	0016020	cellular_component	membrane
I	0022626	cellular_component	cytosolic ribosome
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	0032040	cellular_component	small-subunit processome
I	0042274	biological_process	ribosomal small subunit biogenesis
I	0070062	cellular_component	extracellular exosome
I	1990904	cellular_component	ribonucleoprotein complex
j	0001891	cellular_component	phagocytic cup
j	0001934	biological_process	positive regulation of protein phosphorylation
j	0002181	biological_process	cytoplasmic translation
j	0003723	molecular_function	RNA binding
j	0005080	molecular_function	protein kinase C binding
j	0005102	molecular_function	signaling receptor binding
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005737	cellular_component	cytoplasm
j	0005739	cellular_component	mitochondrion
j	0005829	cellular_component	cytosol
j	0005886	cellular_component	plasma membrane
j	0008047	molecular_function	enzyme activator activity
j	0008200	molecular_function	ion channel inhibitor activity
j	0010629	biological_process	negative regulation of gene expression
j	0015935	cellular_component	small ribosomal subunit
j	0016567	biological_process	protein ubiquitination
j	0017148	biological_process	negative regulation of translation
j	0019899	molecular_function	enzyme binding
j	0019903	molecular_function	protein phosphatase binding
j	0030178	biological_process	negative regulation of Wnt signaling pathway
j	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
j	0030292	molecular_function	protein tyrosine kinase inhibitor activity
j	0030308	biological_process	negative regulation of cell growth
j	0030332	molecular_function	cyclin binding
j	0030335	biological_process	positive regulation of cell migration
j	0030425	cellular_component	dendrite
j	0030496	cellular_component	midbody
j	0030971	molecular_function	receptor tyrosine kinase binding
j	0031334	biological_process	positive regulation of protein-containing complex assembly
j	0032091	biological_process	negative regulation of protein binding
j	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
j	0032880	biological_process	regulation of protein localization
j	0035591	molecular_function	signaling adaptor activity
j	0042169	molecular_function	SH2 domain binding
j	0042802	molecular_function	identical protein binding
j	0042803	molecular_function	protein homodimerization activity
j	0042998	biological_process	positive regulation of Golgi to plasma membrane protein transport
j	0043005	cellular_component	neuron projection
j	0043022	molecular_function	ribosome binding
j	0043025	cellular_component	neuronal cell body
j	0043065	biological_process	positive regulation of apoptotic process
j	0043204	cellular_component	perikaryon
j	0043547	biological_process	positive regulation of GTPase activity
j	0044297	cellular_component	cell body
j	0045182	molecular_function	translation regulator activity
j	0045296	molecular_function	cadherin binding
j	0045879	biological_process	negative regulation of smoothened signaling pathway
j	0048471	cellular_component	perinuclear region of cytoplasm
j	0050765	biological_process	negative regulation of phagocytosis
j	0051302	biological_process	regulation of cell division
j	0051434	molecular_function	BH3 domain binding
j	0051726	biological_process	regulation of cell cycle
j	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
j	0060090	molecular_function	molecular adaptor activity
j	0070062	cellular_component	extracellular exosome
j	0071333	biological_process	cellular response to glucose stimulus
j	0071363	biological_process	cellular response to growth factor stimulus
j	0072344	biological_process	rescue of stalled cytosolic ribosome
j	0106070	biological_process	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
j	1900102	biological_process	negative regulation of endoplasmic reticulum unfolded protein response
j	1903751	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
j	1990630	cellular_component	IRE1-RACK1-PP2A complex
j	2000114	biological_process	regulation of establishment of cell polarity
j	2000543	biological_process	positive regulation of gastrulation
j	2001125	biological_process	negative regulation of translational frameshifting
J	0002181	biological_process	cytoplasmic translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005730	cellular_component	nucleolus
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0005925	cellular_component	focal adhesion
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0016020	cellular_component	membrane
J	0019843	molecular_function	rRNA binding
J	0022626	cellular_component	cytosolic ribosome
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0032040	cellular_component	small-subunit processome
J	0042274	biological_process	ribosomal small subunit biogenesis
J	0045202	cellular_component	synapse
J	0070062	cellular_component	extracellular exosome
J	1990904	cellular_component	ribonucleoprotein complex
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003729	molecular_function	mRNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005654	cellular_component	nucleoplasm
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005783	cellular_component	endoplasmic reticulum
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0005925	cellular_component	focal adhesion
K	0006412	biological_process	translation
K	0006413	biological_process	translational initiation
K	0006450	biological_process	regulation of translational fidelity
K	0015935	cellular_component	small ribosomal subunit
K	0016020	cellular_component	membrane
K	0019843	molecular_function	rRNA binding
K	0022626	cellular_component	cytosolic ribosome
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0032040	cellular_component	small-subunit processome
K	0042274	biological_process	ribosomal small subunit biogenesis
K	0045202	cellular_component	synapse
K	0070062	cellular_component	extracellular exosome
K	1990904	cellular_component	ribonucleoprotein complex
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005654	cellular_component	nucleoplasm
L	0005730	cellular_component	nucleolus
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0005925	cellular_component	focal adhesion
L	0006412	biological_process	translation
L	0016020	cellular_component	membrane
L	0022626	cellular_component	cytosolic ribosome
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	0032040	cellular_component	small-subunit processome
L	0042274	biological_process	ribosomal small subunit biogenesis
L	0045202	cellular_component	synapse
L	0070062	cellular_component	extracellular exosome
N	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003729	molecular_function	mRNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005730	cellular_component	nucleolus
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0005925	cellular_component	focal adhesion
N	0006412	biological_process	translation
N	0014069	cellular_component	postsynaptic density
N	0016020	cellular_component	membrane
N	0022626	cellular_component	cytosolic ribosome
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0032040	cellular_component	small-subunit processome
N	0033119	biological_process	negative regulation of RNA splicing
N	0042274	biological_process	ribosomal small subunit biogenesis
N	0048027	molecular_function	mRNA 5'-UTR binding
N	0070062	cellular_component	extracellular exosome
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005654	cellular_component	nucleoplasm
O	0005730	cellular_component	nucleolus
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0016020	cellular_component	membrane
O	0022626	cellular_component	cytosolic ribosome
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0032040	cellular_component	small-subunit processome
O	0042274	biological_process	ribosomal small subunit biogenesis
O	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
O	1990145	biological_process	maintenance of translational fidelity
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0015935	cellular_component	small ribosomal subunit
R	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005654	cellular_component	nucleoplasm
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0005783	cellular_component	endoplasmic reticulum
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0005925	cellular_component	focal adhesion
R	0006364	biological_process	rRNA processing
R	0006412	biological_process	translation
R	0015935	cellular_component	small ribosomal subunit
R	0016020	cellular_component	membrane
R	0022626	cellular_component	cytosolic ribosome
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	0032040	cellular_component	small-subunit processome
R	0042274	biological_process	ribosomal small subunit biogenesis
R	0045202	cellular_component	synapse
R	0070062	cellular_component	extracellular exosome
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005654	cellular_component	nucleoplasm
S	0005730	cellular_component	nucleolus
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0005925	cellular_component	focal adhesion
S	0006364	biological_process	rRNA processing
S	0006412	biological_process	translation
S	0006413	biological_process	translational initiation
S	0016020	cellular_component	membrane
S	0022626	cellular_component	cytosolic ribosome
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	0032040	cellular_component	small-subunit processome
S	0034101	biological_process	erythrocyte homeostasis
S	0042274	biological_process	ribosomal small subunit biogenesis
S	0045202	cellular_component	synapse
T	0002181	biological_process	cytoplasmic translation
T	0003676	molecular_function	nucleic acid binding
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0005925	cellular_component	focal adhesion
T	0006412	biological_process	translation
T	0014069	cellular_component	postsynaptic density
T	0015935	cellular_component	small ribosomal subunit
T	0016020	cellular_component	membrane
T	0022626	cellular_component	cytosolic ribosome
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0045202	cellular_component	synapse
T	0070062	cellular_component	extracellular exosome
u	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
u	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
u	0003723	molecular_function	RNA binding
u	0003924	molecular_function	GTPase activity
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005730	cellular_component	nucleolus
u	0005829	cellular_component	cytosol
u	0030686	cellular_component	90S preribosome
u	0042254	biological_process	ribosome biogenesis
U	0000028	biological_process	ribosomal small subunit assembly
U	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
U	0002181	biological_process	cytoplasmic translation
U	0002548	biological_process	monocyte chemotaxis
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005654	cellular_component	nucleoplasm
U	0005730	cellular_component	nucleolus
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0005925	cellular_component	focal adhesion
U	0006364	biological_process	rRNA processing
U	0006412	biological_process	translation
U	0007000	biological_process	nucleolus organization
U	0014069	cellular_component	postsynaptic density
U	0016020	cellular_component	membrane
U	0017134	molecular_function	fibroblast growth factor binding
U	0022626	cellular_component	cytosolic ribosome
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	0030218	biological_process	erythrocyte differentiation
U	0030490	biological_process	maturation of SSU-rRNA
U	0031640	biological_process	killing of cells of another organism
U	0032040	cellular_component	small-subunit processome
U	0042274	biological_process	ribosomal small subunit biogenesis
U	0042802	molecular_function	identical protein binding
U	0050829	biological_process	defense response to Gram-negative bacterium
U	0060265	biological_process	positive regulation of respiratory burst involved in inflammatory response
U	0060266	biological_process	negative regulation of respiratory burst involved in inflammatory response
U	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
U	0070062	cellular_component	extracellular exosome
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0015935	cellular_component	small ribosomal subunit
W	0002181	biological_process	cytoplasmic translation
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005515	molecular_function	protein binding
W	0005654	cellular_component	nucleoplasm
W	0005730	cellular_component	nucleolus
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0008284	biological_process	positive regulation of cell population proliferation
W	0009615	biological_process	response to virus
W	0016020	cellular_component	membrane
W	0022626	cellular_component	cytosolic ribosome
W	0022627	cellular_component	cytosolic small ribosomal subunit
W	0032040	cellular_component	small-subunit processome
W	0042274	biological_process	ribosomal small subunit biogenesis
W	0045202	cellular_component	synapse
W	0045787	biological_process	positive regulation of cell cycle
W	0070062	cellular_component	extracellular exosome
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005654	cellular_component	nucleoplasm
X	0005730	cellular_component	nucleolus
X	0005737	cellular_component	cytoplasm
X	0005791	cellular_component	rough endoplasmic reticulum
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0015935	cellular_component	small ribosomal subunit
X	0016020	cellular_component	membrane
X	0022626	cellular_component	cytosolic ribosome
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	0032040	cellular_component	small-subunit processome
X	0034063	biological_process	stress granule assembly
X	0042274	biological_process	ribosomal small subunit biogenesis
X	0045202	cellular_component	synapse
X	1990145	biological_process	maintenance of translational fidelity
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005783	cellular_component	endoplasmic reticulum
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006364	biological_process	rRNA processing
Y	0006412	biological_process	translation
Y	0015935	cellular_component	small ribosomal subunit
Y	0016020	cellular_component	membrane
Y	0022626	cellular_component	cytosolic ribosome
Y	0022627	cellular_component	cytosolic small ribosomal subunit
Y	0031369	molecular_function	translation initiation factor binding
Y	0032040	cellular_component	small-subunit processome
Y	0034101	biological_process	erythrocyte homeostasis
Y	0042274	biological_process	ribosomal small subunit biogenesis
Z	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005515	molecular_function	protein binding
Z	0005654	cellular_component	nucleoplasm
Z	0005737	cellular_component	cytoplasm
Z	0005791	cellular_component	rough endoplasmic reticulum
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0015935	cellular_component	small ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	0022627	cellular_component	cytosolic small ribosomal subunit
Z	0045202	cellular_component	synapse

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN c 201

Chain	Residue
c	CYS23
c	CYS26
c	CYS74
c	CYS77

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN f 201

Chain	Residue
f	CYS21
f	CYS24
f	CYS39
f	CYS42

---

site_id	AC3
Number of Residues	3
Details	binding site for residue ZN g 500

Chain	Residue
g	CYS126
g	LYS143
g	GLU125

---

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
K	GLU70-ALA96

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR

Chain	Residue	Details
W	GLY100-ARG117

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD

Chain	Residue	Details
P	LEU116-ASP138

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
X	LYS60-ARG67

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS

Chain	Residue	Details
L	GLY123-SER135

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
Q	ASN98-THR122

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
R	GLY74-LEU92

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
V	ALA43-THR58

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
N	VAL98-TYR128

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
f	ARG22-ARG44

---

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK

Chain	Residue	Details
E	HIS8-LYS22

---

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE

Chain	Residue	Details
Y	PHE64-GLU86

---

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
F	ALA147-GLY183

---

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
G	ILE52-MET63

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI

Chain	Residue	Details
D	GLY119-ILE151

---

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
U	PRO89-GLU108

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI

Chain	Residue	Details
J	LEU106-ILE130

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
T	ARG121-GLN134

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
j	ALA78-LEU92
j	ILE120-THR134
j	ILE165-LEU179
j	CYS207-LEU221

---

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
S	ILE41-HIS56

---

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH

Chain	Residue	Details
c	TYR73-HIS80

---

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH

Chain	Residue	Details
H	ARG78-HIS91

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
d	GLU60-LEU68

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG

Chain	Residue	Details
B	VAL15-GLY26

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP

Chain	Residue	Details
B	PRO119-PRO143

---

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
Z	LEU11-ALA19

---

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG

Chain	Residue	Details
b	LYS36-GLY68

---

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI

Chain	Residue	Details
O	ALA17-ILE35

---

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL

Chain	Residue	Details
C	LEU62-LEU74

---

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG

Chain	Residue	Details
I	ARG11-GLY30

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	59
Details	Region: {"description":"Interaction with PPP1R16B","evidences":[{"source":"PubMed","id":"16263087","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	19
Details	Region: {"description":"Laminin-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Cleavage; by ST3; site 1","evidences":[{"source":"HAMAP-Rule","id":"MF_03016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Site: {"description":"Cleavage; by ST3; site 2","evidences":[{"source":"HAMAP-Rule","id":"MF_03016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"HAMAP-Rule","id":"MF_03016","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Potts A.","Barblan J.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	16
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	18
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P14206","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	11
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P97351","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"ADP-ribosyltyrosine","evidences":[{"source":"PubMed","id":"29954836","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	63
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00268","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"28132843","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	62
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62702","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	24
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	71
Details	Domain: {"description":"KH type-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00118","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PKC/PRKCD","evidences":[{"source":"PubMed","id":"19059439","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by MAPK","evidences":[{"source":"PubMed","id":"15950189","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	3
Details	Modified residue: {"description":"Asymmetric dimethylarginine; by PRMT1","evidences":[{"source":"PubMed","id":"19460357","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by PKB","evidences":[{"source":"PubMed","id":"20605787","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62908","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by IKKB","evidences":[{"source":"PubMed","id":"21399639","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by CDK1 and PKC/PRKCD","evidences":[{"source":"PubMed","id":"19059439","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21871177","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2009","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Waridel P.","Quadroni M."]}},{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16807684","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"28065601","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28132843","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31981475","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32011234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34348161","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34469731","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39609413","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39947182","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	22
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	Modified residue: {"description":"ADP-ribosyl glutamic acid","evidences":[{"source":"PubMed","id":"34314702","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	1
Details	Modified residue: {"description":"(3R)-3-hydroxyarginine","evidences":[{"source":"PubMed","id":"29563586","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	58
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62242","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	1
Details	Lipidation: {"description":"N-myristoyl glycine","evidences":[{"source":"PubMed","id":"25255805","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q6ZWN5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2006","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Kanor S.","Tissot J.-D.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	1
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P62281","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62281","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"P62281","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"21044946","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P63325","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62301","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62301","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P63323","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	46
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P63276","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	2
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9CZX8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q9CZX8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P60867","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62245","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62267","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	1
Details	Modified residue: {"description":"3-hydroxyproline","evidences":[{"source":"PubMed","id":"24550447","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24550462","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28257692","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2006","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Kanor S.","Tissot J.-D.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62852","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62852","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	22
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI68
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34516797","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MQ8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI69
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI70
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62862","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI71
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI72
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FLX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LKS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI73
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LKS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI74
Number of Residues	23
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"32129764","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	31
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI78
Number of Residues	30
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	30
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	32
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI81
Number of Residues	30
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI82
Number of Residues	29
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI83
Number of Residues	30
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI84
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine; in Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2006","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Kanor S.","Tissot J.-D.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI85
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1","evidences":[{"source":"PubMed","id":"19423701","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI86
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P68040","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI87
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"11279199","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI88
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI89
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI90
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI91
Number of Residues	26
Details	Region: {"description":"Binding to 40s ribosome mRNA entry channel","evidences":[{"source":"PubMed","id":"32680882","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32908316","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---