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6ZL3

CRYSTAL STRUCTURE OF HRAS IN COMPLEX WITH COMPOUND 18 and GDP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTPase HRaspolymer16718932.21UniProt (P01112)
Pfam (PF00071)
Homo sapiens (Human)H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras
2B
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
3C
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
4D
(A)
(3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-onenon-polymer321.41Chemie (EZZ)
5E
(A)
waterwater18.0118Chemie (HOH)
Sequence modifications
A: 1 - 166 (UniProt: P01112)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18932.2
Non-Polymers*Number of molecules3
Total formula weight787.6
All*Total formula weight19719.8
*Water molecules are not included.

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PDB entries from 2026-02-25

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