6ZKZ
Crystal structure of InhA:01 TCR in complex with HLA-E (F116C) bound to InhA (53-61 H4C)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, alpha chain E | polymer | 276 | 31780.0 | 1 | UniProt (P13747) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | MHC class I antigen E |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 9 | 1012.3 | 1 | UniProt (by SIFTS) (P9WGR1) | Mycobacterium tuberculosis H37Rv | |
| 4 | D (D) | T-cell receptor alpha chain | polymer | 199 | 21496.7 | 1 | Homo sapiens (Human) | ||
| 5 | E (E) | T-cell receptor beta chain | polymer | 245 | 27491.5 | 1 | Homo sapiens (Human) | ||
| 6 | F, G, H, I (A, B, D, E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | J, K, L, M, N (A, B, C, D, E) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P13747)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Cys 116 | Phe 137 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 93659.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 248.3 | |
| All* | Total formula weight | 93908.2 |
