6ZJF

Crystal structure of STK17B (DRAK2) in complex with AP-229

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Serine/threonine-protein kinase 17B	polymer	327	37327.1	1	UniProt (O94768) Pfam (PF00069) In PDB	Homo sapiens (Human)	DAP kinase-related apoptosis-inducing protein kinase 2
2	A	2-[6-(4-cyclopropylphenyl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic acid	non-polymer		342.4	1	Chemie (QM2)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4		water	water		18.0	231	Chemie (HOH)

Sequence modifications

A: 25 - 329 (UniProt: O94768)

PDB	External Database	Details
Met 3	-	initiating methionine
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Ser 10	-	expression tag
Ser 11	-	expression tag
Gly 12	-	expression tag
Val 13	-	expression tag
Asp 14	-	expression tag
Leu 15	-	expression tag
Gly 16	-	expression tag
Thr 17	-	expression tag
Glu 18	-	expression tag
Asn 19	-	expression tag
Leu 20	-	expression tag
Tyr 21	-	expression tag
Phe 22	-	expression tag
Gln 23	-	expression tag
Ser 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37327.1
Non-Polymers*	Number of molecules	3
	Total formula weight	466.6
All*	Total formula weight	37793.7

*Water molecules are not included.