6ZIR
CRYSTAL STRUCTURE OF NRAS (C118S) IN COMPLEX WITH GDP AND COMPOUND 18
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | GTPase NRas | polymer | 173 | 19612.2 | 1 | UniProt (P01111) Pfam (PF00071) In PDB | Homo sapiens (Human) | Transforming protein N-Ras |
| 2 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | A | (3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one | non-polymer | 321.4 | 2 | Chemie (EZZ) | |||
| 5 | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A: 1 - 172 (UniProt: P01111)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 118 | Cys 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19612.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1134.6 | |
| All* | Total formula weight | 20746.8 |
