6ZG0

SARM1 SAM1-2 domains

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	NAD(+) hydrolase SARM1	polymer	726	79971.3	8	UniProt (Q6SZW1) Pfam (PF07647) Pfam (PF13676)	Homo sapiens (Human)	hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog,HsTIR
2	AA, BA, CA, DA, EA... (D, E, F, A, B...)	1,2-ETHANEDIOL	non-polymer		62.1	17	Chemie (EDO)
3	FA, HA, IA, J, JA... (E, F, G, A, H...)	BETA-MERCAPTOETHANOL	non-polymer		78.1	8	Chemie (BME)
4	N, X (B, D)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
5	P (B)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)

Sequence modifications

A, B, C, D, E, F, G, H: 26 - 724 (UniProt: Q6SZW1)

PDB	External Database	Details
Met -1	-	initiating methionine
Ser 0	-	expression tag
Tyr 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
Asp 8	-	expression tag
Tyr 9	-	expression tag
Asp 10	-	expression tag
Ile 11	-	expression tag
Pro 12	-	expression tag
Thr 13	-	expression tag
Thr 14	-	expression tag
Glu 15	-	expression tag
Asn 16	-	expression tag
Leu 17	-	expression tag
Tyr 18	-	expression tag
Phe 19	-	expression tag
Gln 20	-	expression tag
Gly 21	-	expression tag
Ala 22	-	expression tag
Met 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
Gln 642	Glu 642	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	639770.1
Non-Polymers*	Number of molecules	28
	Total formula weight	2042.6
All*	Total formula weight	641812.7

*Water molecules are not included.