6ZFX

hSARM1 GraFix-ed

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	NAD(+) hydrolase SARM1	polymer	726	79971.3	8	UniProt (Q6SZW1) Pfam (PF07647) Pfam (PF13676) In PDB	Homo sapiens (Human)	hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog,HsTIR
2	A, B, C, D, E...	(~{E})-4-methylnon-4-enedial	non-polymer		168.2	16	Chemie (S1N)

Sequence modifications

A, B, C, D, E, F, G, H: 26 - 724 (UniProt: Q6SZW1)

PDB	External Database	Details
Met -1	-	initiating methionine
Ser 0	-	expression tag
Tyr 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
Asp 8	-	expression tag
Tyr 9	-	expression tag
Asp 10	-	expression tag
Ile 11	-	expression tag
Pro 12	-	expression tag
Thr 13	-	expression tag
Thr 14	-	expression tag
Glu 15	-	expression tag
Asn 16	-	expression tag
Leu 17	-	expression tag
Tyr 18	-	expression tag
Phe 19	-	expression tag
Gln 20	-	expression tag
Gly 21	-	expression tag
Ala 22	-	expression tag
Met 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
Gln 642	Glu 642	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	639770.1
Non-Polymers*	Number of molecules	16
	Total formula weight	2691.7
All*	Total formula weight	642461.8

*Water molecules are not included.