6ZFN
Structure of an inactive E404Q variant of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with 1-methyl alpha-1,2-mannobiose
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA | Glycoprotein endo-alpha-1,2-mannosidase | polymer | 382 | 44782.1 | 1 | UniProt (Q5SRI9) Pfam (PF16317) In PDB | Homo sapiens (Human) | hEndo,Mandaselin |
2 | A | alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside | branched | 356.3 | 1 | In PDB GlyTouCan (G49351KY) | |||
3 | AAA | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | water | water | 18.0 | 478 | Chemie (HOH) |
Sequence modifications
AAA: 98 - 462 (UniProt: Q5SRI9)
PDB | External Database | Details |
---|---|---|
Met 81 | - | initiating methionine |
Asn 82 | - | expression tag |
His 83 | - | expression tag |
Lys 84 | - | expression tag |
Val 85 | - | expression tag |
His 86 | - | expression tag |
His 87 | - | expression tag |
His 88 | - | expression tag |
His 89 | - | expression tag |
His 90 | - | expression tag |
His 91 | - | expression tag |
Ile 92 | - | expression tag |
Glu 93 | - | expression tag |
Gly 94 | - | expression tag |
Arg 95 | - | expression tag |
His 96 | - | expression tag |
Met 97 | - | expression tag |
Gln 404 | Glu 404 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44782.1 | |
Branched | Number of molecules | 1 |
Total formula weight | 356.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 96.1 | |
All* | Total formula weight | 45234.5 |