6ZFA
Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG, alpha-1,2-mannobiose and hexatungstotellurate(VI) TEW
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA | Glycoprotein endo-alpha-1,2-mannosidase | polymer | 382 | 44783.1 | 1 | UniProt (Q5SRI9) Pfam (PF16317) In PDB | Homo sapiens (Human) | hEndo,Mandaselin |
2 | A | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900111) GlyTouCan (G53402KW) | 2alpha-alpha-mannobiose | ||
3 | AAA | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
4 | AAA | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | AAA | 6-tungstotellurate(VI) | non-polymer | 1614.6 | 3 | Chemie (TEW) | |||
6 | AAA | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE | non-polymer | 147.2 | 1 | Chemie (IFM) | |||
7 | AAA | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
8 | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
AAA: 98 - 462 (UniProt: Q5SRI9)
PDB | External Database | Details |
---|---|---|
Met 81 | - | initiating methionine |
Asn 82 | - | expression tag |
His 83 | - | expression tag |
Lys 84 | - | expression tag |
Val 85 | - | expression tag |
His 86 | - | expression tag |
His 87 | - | expression tag |
His 88 | - | expression tag |
His 89 | - | expression tag |
His 90 | - | expression tag |
His 91 | - | expression tag |
Ile 92 | - | expression tag |
Glu 93 | - | expression tag |
Gly 94 | - | expression tag |
Arg 95 | - | expression tag |
His 96 | - | expression tag |
Met 97 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44783.1 | |
Branched | Number of molecules | 1 |
Total formula weight | 342.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 5433.8 | |
All* | Total formula weight | 50559.2 |