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6ZEX

Keap1 kelch domain bound to a small molecule fragment

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Kelch-like ECH-associated protein 1polymer30433362.31UniProt (Q9Z2X8)
Pfam (PF01344)
Mus musculus (House mouse)Cytosolic inhibitor of Nrf2,INrf2
2B, C, D, E, F...
(A)
DIMETHYL SULFOXIDEnon-polymer78.16Chemie (DMS)
3H
(A)
5-cyclopropyl-1-phenyl-pyrazole-4-carboxylic acidnon-polymer228.21Chemie (QHN)
4I
(A)
waterwater18.045Chemie (HOH)
Sequence modifications
A: 322 - 624 (UniProt: Q9Z2X8)
PDBExternal DatabaseDetails
Gly 321-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33362.3
Non-Polymers*Number of molecules7
Total formula weight697.0
All*Total formula weight34059.3
*Water molecules are not included.

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PDB entries from 2025-09-24

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