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6ZBU

Crystal structure of an NCoR1BBD2-BCL6BTB chimera in complex with the NcoR1 BBD1 corepressor peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, E, F, I...Nuclear receptor corepressor 1,B-cell lymphoma 6 proteinpolymer13715603.06UniProt (O75376)
UniProt (P41182)
Pfam (PF00651)
In PDB
Homo sapiens (Human)N-CoR1,BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51
2C, D, G, K, L...Nuclear receptor corepressor 1polymer171942.36UniProt (O75376)
In PDB
Homo sapiensN-CoR1
3E, F, G, I, J...SULFATE IONnon-polymer96.128Chemie (SO4)
4I, A, C, DGLYCEROLnon-polymer92.14Chemie (GOL)
5waterwater18.0120Chemie (HOH)
Sequence modifications
A, B, E, F, I, J: -5 - 3 (UniProt: O75376)
PDBExternal DatabaseDetails
Gly -7-expression tag
Pro -6-expression tag
Gly 4-linker
Gly 5-linker
A, B, E, F, I, J: 6 - 129 (UniProt: P41182)
PDBExternal DatabaseDetails
Gln 8Cys 8conflict
Arg 67Cys 67conflict
Asn 84Cys 84conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight105271.6
Non-Polymers*Number of molecules32
Total formula weight3058.1
All*Total formula weight108329.8
*Water molecules are not included.

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PDB entries from 2024-06-12

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