6ZBO
HIF Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with 1-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-ol (Molidustat)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Egl nine homolog 1 | polymer | 227 | 25465.0 | 6 | UniProt (Q9GZT9) Pfam (PF13640) | Homo sapiens (Human) | Hypoxia-inducible factor prolyl hydroxylase 2,HIF-PH2,HIF-prolyl hydroxylase 2,HPH-2,Prolyl hydroxylase domain-containing protein 2,PHD2,SM-20 |
| 2 | AA, G, L, P, S... (F, A, B, C, D...) | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 3 | BA, H, M, Q, T... (F, A, B, C, D...) | 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)pyrazol-3-ol | non-polymer | 314.3 | 6 | Chemie (QEQ) | |||
| 4 | CA, DA, EA, I, J... (F, A, B, C, D...) | CHLORIDE ION | non-polymer | 35.5 | 13 | Chemie (CL) | |||
| 5 | FA, GA, HA, IA, JA... (A, B, C, D, E...) | water | water | 18.0 | 622 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 152789.7 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2676.3 | |
| All* | Total formula weight | 155466.1 |
