6ZBO

HIF Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with 1-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-ol (Molidustat)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Egl nine homolog 1	polymer	227	25465.0	6	UniProt (Q9GZT9) Pfam (PF13640) In PDB	Homo sapiens (Human)	Hypoxia-inducible factor prolyl hydroxylase 2,HIF-PH2,HIF-prolyl hydroxylase 2,HPH-2,Prolyl hydroxylase domain-containing protein 2,PHD2,SM-20
2	F, A, B, C, D...	MANGANESE (II) ION	non-polymer		54.9	6	Chemie (MN)
3	F, A, B, C, D...	2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)pyrazol-3-ol	non-polymer		314.3	6	Chemie (QEQ)
4	F, A, B, C, D...	CHLORIDE ION	non-polymer		35.5	13	Chemie (CL)
5		water	water		18.0	622	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	152789.7
Non-Polymers*	Number of molecules	25
	Total formula weight	2676.3
All*	Total formula weight	155466.1

*Water molecules are not included.