6ZBN
HIF Prolyl Hydroxylase 2 (PHD2/EGLN1) in complex with tert-butyl 6-(5-hydroxy-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-1-yl)nicotinate (IOX4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Egl nine homolog 1 | polymer | 227 | 25465.0 | 6 | UniProt (Q9GZT9) Pfam (PF13640) | Homo sapiens (Human) | Hypoxia-inducible factor prolyl hydroxylase 2,HIF-PH2,HIF-prolyl hydroxylase 2,HPH-2,Prolyl hydroxylase domain-containing protein 2,PHD2,SM-20 |
| 2 | G, I, K, N, P... (A, B, C, D, E...) | ~{tert}-butyl 6-[5-oxidanyl-4-(1,2,3-triazol-1-yl)pyrazol-1-yl]pyridine-3-carboxylate | non-polymer | 328.3 | 6 | Chemie (QEE) | |||
| 3 | H, J, M, O, Q... (A, B, C, D, E...) | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 4 | L (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | T, U, V, W, X... (A, B, C, D, E...) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 152789.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2391.7 | |
| All* | Total formula weight | 155181.4 |
