6Z8V
X-ray structure of the complex between human alpha thrombin and a thrombin binding aptamer variant (TBA-3L), which contains 1-beta-D-lactopyranosyl residue in the side chain of Thy3 at N3.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | Prothrombin | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (Human) | Coagulation factor II |
| 2 | H | Prothrombin | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (Human) | Coagulation factor II |
| 3 | A | TBA-3L | polymer | 15 | 4824.1 | 1 | synthetic construct | ||
| 4 | H | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 1 | Chemie (0G6) | |||
| 5 | H | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 7 | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38700.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 516.1 | |
| All* | Total formula weight | 39217.0 |
