6Z8C
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with N-desmethyltamoxifen (3.2 A resolution)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ion transport protein | polymer | 277 | 31185.7 | 1 | UniProt (A0L5S6) Pfam (PF00520) Pfam (PF08016) | Magnetococcus marinus MC-1 | |
| 2 | B, C, D (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 3 | E, G (A) | HEGA-10 | non-polymer | 379.5 | 2 | Chemie (2CV) | |||
| 4 | F (A) | DODECAETHYLENE GLYCOL | non-polymer | 546.6 | 1 | Chemie (12P) | |||
| 5 | H, I (A) | 2-[4-[(~{Z})-1,2-diphenylbut-1-enyl]phenoxy]-~{N}-methyl-ethanamine | non-polymer | 357.5 | 2 | Chemie (QBN) | |||
| 6 | J (A) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A: 1 - 274 (UniProt: A0L5S6)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Leu 208 | Phe 208 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31185.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2089.6 | |
| All* | Total formula weight | 33275.3 |
