6Z87

human GTP cyclohydrolase I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	GTP cyclohydrolase 1	polymer	224	25324.9	5	UniProt (P30793) Pfam (PF01227)	Homo sapiens (Human)	GTP cyclohydrolase I,GTP-CH-I
2	F, G, H, I, J (A, B, C, D, E)	ZINC ION	non-polymer		65.4	5	Chemie (ZN)
3	K, L, M, N, O (A, B, C, D, E)	water	water		18.0	86	Chemie (HOH)

Sequence modifications

A, B, C, D, E: 41 - 250 (UniProt: P30793)

PDB	External Database	Details
Met 27	-	initiating methionine
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
Gly 34	-	expression tag
Ser 35	-	expression tag
Asp 36	-	expression tag
Asp 37	-	expression tag
Asp 38	-	expression tag
Asp 39	-	expression tag
Lys 40	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	126624.6
Non-Polymers*	Number of molecules	5
	Total formula weight	327.0
All*	Total formula weight	126951.6

*Water molecules are not included.