6Z87

human GTP cyclohydrolase I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003934	molecular_function	GTP cyclohydrolase I activity
A	0046654	biological_process	tetrahydrofolate biosynthetic process
B	0003934	molecular_function	GTP cyclohydrolase I activity
B	0046654	biological_process	tetrahydrofolate biosynthetic process
C	0003934	molecular_function	GTP cyclohydrolase I activity
C	0046654	biological_process	tetrahydrofolate biosynthetic process
D	0003934	molecular_function	GTP cyclohydrolase I activity
D	0046654	biological_process	tetrahydrofolate biosynthetic process
E	0003934	molecular_function	GTP cyclohydrolase I activity
E	0046654	biological_process	tetrahydrofolate biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00859
Number of Residues	17
Details	GTP_CYCLOHYDROL_1_1 GTP cyclohydrolase I signature 1. EMVivKDIdmfSmCEHH

Chain	Residue	Details
A	GLU128-HIS144

---

site_id	PS00860
Number of Residues	11
Details	GTP_CYCLOHYDROL_1_2 GTP cyclohydrolase I signature 2. SrRlQVQERLT

Chain	Residue	Details
A	SER176-THR186

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	BINDING: BINDING => ECO:0000269|PubMed:11087827

Chain	Residue	Details
A	CYS141
D	CYS141
D	HIS144
D	CYS212
E	CYS141
E	HIS144
E	CYS212
A	HIS144
A	CYS212
B	CYS141
B	HIS144
B	CYS212
C	CYS141
C	HIS144
C	CYS212

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	SER60
B	SER60
C	SER60
D	SER60
E	SER60

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:17704208

Chain	Residue	Details
A	SER81
B	SER81
C	SER81
D	SER81
E	SER81

---