6Z7V
Crystal structure of Mindy2 (C266A) in complex with Lys48 linked di-ubiquitin (K48-Ub2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ubiquitin carboxyl-terminal hydrolase MINDY-2 | polymer | 273 | 31168.4 | 2 | UniProt (Q8NBR6) Pfam (PF04424) | Homo sapiens (Human) | Deubiquitinating enzyme MINDY-2,Protein FAM63B |
| 2 | C, D, E, F, G... (C, D, E, F, G...) | Polyubiquitin-C | polymer | 76 | 8576.8 | 7 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (Human) | |
| 3 | J, L, M, P (A, B, G) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | K, N, O (A, B, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 5 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A, B: 241 - 504 (UniProt: Q8NBR6)
| PDB | External Database | Details |
|---|---|---|
| Gly 232 | - | expression tag |
| Pro 233 | - | expression tag |
| Leu 234 | - | expression tag |
| Gly 235 | - | expression tag |
| Ser 236 | - | expression tag |
| Pro 237 | - | expression tag |
| Glu 238 | - | expression tag |
| Phe 239 | - | expression tag |
| Met 240 | - | expression tag |
| Ala 266 | Cys 266 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 122374.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 739.1 | |
| All* | Total formula weight | 123113.7 |
