Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
A | 1990380 | molecular_function | K48-linked deubiquitinase activity |
B | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
B | 1990380 | molecular_function | K48-linked deubiquitinase activity |
Functional Information from PROSITE/UniProt
site_id | PS00299 |
Number of Residues | 26 |
Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
Chain | Residue | Details |
C | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 14 |
Details | SITE: Interacts with activating enzyme |
Chain | Residue | Details |
C | ARG54 | |
G | ARG72 | |
H | ARG54 | |
H | ARG72 | |
I | ARG54 | |
I | ARG72 | |
C | ARG72 | |
D | ARG54 | |
D | ARG72 | |
E | ARG54 | |
E | ARG72 | |
F | ARG54 | |
F | ARG72 | |
G | ARG54 | |
site_id | SWS_FT_FI2 |
Number of Residues | 7 |
Details | SITE: Essential for function |
Chain | Residue | Details |
C | HIS68 | |
D | HIS68 | |
E | HIS68 | |
F | HIS68 | |
G | HIS68 | |
H | HIS68 | |
I | HIS68 | |
Chain | Residue | Details |
C | SER65 | |
D | SER65 | |
E | SER65 | |
F | SER65 | |
G | SER65 | |
H | SER65 | |
I | SER65 | |
Chain | Residue | Details |
C | THR66 | |
D | THR66 | |
E | THR66 | |
F | THR66 | |
G | THR66 | |
H | THR66 | |
I | THR66 | |
Chain | Residue | Details |
C | GLY76 | |
D | GLY76 | |
E | GLY76 | |
F | GLY76 | |
G | GLY76 | |
H | GLY76 | |
I | GLY76 | |
site_id | SWS_FT_FI6 |
Number of Residues | 7 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603 |
Chain | Residue | Details |
C | LYS6 | |
D | LYS6 | |
E | LYS6 | |
F | LYS6 | |
G | LYS6 | |
H | LYS6 | |
I | LYS6 | |
site_id | SWS_FT_FI7 |
Number of Residues | 14 |
Details | CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) |
Chain | Residue | Details |
G | GLY76 | |
H | GLY76 | |
I | GLY76 | |
C | GLY76 | |
D | GLY76 | |
E | GLY76 | |
F | GLY76 | |
Chain | Residue | Details |
C | LYS11 | |
G | LYS48 | |
H | LYS11 | |
H | LYS48 | |
I | LYS11 | |
I | LYS48 | |
C | LYS48 | |
D | LYS11 | |
D | LYS48 | |
E | LYS11 | |
E | LYS48 | |
F | LYS11 | |
F | LYS48 | |
G | LYS11 | |
site_id | SWS_FT_FI9 |
Number of Residues | 7 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 |
Chain | Residue | Details |
C | LYS27 | |
D | LYS27 | |
E | LYS27 | |
F | LYS27 | |
G | LYS27 | |
H | LYS27 | |
I | LYS27 | |
Chain | Residue | Details |
C | LYS29 | |
D | LYS29 | |
E | LYS29 | |
F | LYS29 | |
G | LYS29 | |
H | LYS29 | |
I | LYS29 | |
site_id | SWS_FT_FI11 |
Number of Residues | 7 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 |
Chain | Residue | Details |
C | LYS33 | |
D | LYS33 | |
E | LYS33 | |
F | LYS33 | |
G | LYS33 | |
H | LYS33 | |
I | LYS33 | |
Chain | Residue | Details |
C | LYS63 | |
D | LYS63 | |
E | LYS63 | |
F | LYS63 | |
G | LYS63 | |
H | LYS63 | |
I | LYS63 | |