6Z48
Crystal structure of Thrombin in complex with macrocycle X1vE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (L, A, C, E) | Thrombin light chain | polymer | 36 | 4096.5 | 4 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (Human) | |
| 2 | B, D, F, H (H, B, D, F) | Thrombin heavy chain | polymer | 259 | 29780.2 | 4 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (Human) | |
| 3 | I, K, M, O (H, B, D, F) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | J, L, N, P (H, B, D, F) | 5-chloranyl-N-[[(4S,15R)-2,5,13,16-tetrakis(oxidanylidene)-15-propan-2-yl-9,10-dithia-3,6,14,17-tetrazabicyclo[17.3.1]tricosa-1(22),19(23),20-trien-4-yl]methyl]thiophene-2-carboxamide | non-polymer | 626.2 | 4 | Chemie (X1V) | |||
| 5 | Q, R, S, T, U... (L, H, A, B, C...) | water | water | 18.0 | 399 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 135507.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2596.8 | |
| All* | Total formula weight | 138103.8 |
