6Z2F

Crystal structure of human AGX1 mutant complexed with UDPGLCNAC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	UDP-N-acetylhexosamine pyrophosphorylase	polymer	509	57547.5	1	UniProt (Q16222) Pfam (PF01704)	Homo sapiens (Human)	Antigen X,AGX,Sperm-associated antigen 2
2	B (B)	UDP-N-acetylhexosamine pyrophosphorylase	polymer	509	57604.5	1	UniProt (Q16222) Pfam (PF01704)	Homo sapiens (Human)	Antigen X,AGX,Sperm-associated antigen 2
3	C, D (A, B)	URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE	non-polymer		607.4	2	Chemie (UD1)
4	E, F (A, B)	water	water		18.0	701	Chemie (HOH)

Sequence modifications

A: 1 - 505 (UniProt: Q16222)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Leu 0	-	expression tag
Tyr 61	His 61	conflict
Thr 229	Ala 229	engineered mutation

B: 1 - 505 (UniProt: Q16222)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Leu 0	-	expression tag
Tyr 61	His 61	conflict
Thr 229	Ala 229	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	115152.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1214.7
All*	Total formula weight	116366.7

*Water molecules are not included.