6Z1V

Structure of the EC2 domain of CD9 in complex with nanobody 4E8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CD9 antigen	polymer	89	10129.4	1	UniProt (P21926) Pfam (PF00335) In PDB	Homo sapiens (Human)	5H9 antigen,Cell growth-inhibiting gene 2 protein,Leukocyte antigen MIC3,Motility-related protein,MRP-1,Tetraspanin-29,Tspan-29,p24
2	B	Nanobody 4E8	polymer	142	15546.3	1		Lama glama (Llama)
3	A	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
4	B	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	B	ACETIC ACID	non-polymer		60.1	1	Chemie (ACY)
6		water	water		18.0	134	Chemie (HOH)

Sequence modifications

A: 114 - 191 (UniProt: P21926)

PDB	External Database	Details
Gly 112	-	expression tag
Ser 113	-	expression tag
Ala 192	-	expression tag
Ala 193	-	expression tag
Ala 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	25675.7
Non-Polymers*	Number of molecules	3
	Total formula weight	272.3
All*	Total formula weight	25948.0

*Water molecules are not included.