6YZ1
The crystal structure of SARS-CoV-2 nsp10-nsp16 methyltransferase complex with Sinefungin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | nsp16 | polymer | 299 | 33486.4 | 1 | UniProt (P0DTD1) Pfam (PF06460) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | pp1ab,ORF1ab polyprotein,nsp16 |
2 | B (B) | nsp10 | polymer | 123 | 13126.1 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | pp1ab,ORF1ab polyprotein,nsp10 |
3 | C (A) | SINEFUNGIN | non-polymer | 381.4 | 1 | Chemie (SFG) | |||
4 | D (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
5 | E, F (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
6 | G, H (A, B) | water | water | 18.0 | 261 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P0DTD1)
B: 10 - 131 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Met 9 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 46612.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 707.4 | |
All* | Total formula weight | 47320.0 |