6YX5
Structure of DrrA from Legionella pneumophilia in complex with human Rab8a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ras-related protein Rab-8A | polymer | 174 | 20042.1 | 1 | UniProt (A0A1U7REJ8) Pfam (PF00071) UniProt (by SIFTS) (P61006) | Homo sapiens (Human) | |
| 2 | B (B) | Multifunctional virulence effector protein DrrA | polymer | 340 | 38837.3 | 1 | UniProt (Q29ST3) Pfam (PF20879) | Legionella pneumophila | |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 5 | E, I, J (A, B) | alpha-D-glucopyranose | non-polymer | 180.2 | 3 | Chemie (GLC) | |||
| 6 | F (A) | [(2~{R},3~{S},4~{R},5~{R})-5-[4-(acetamidomethyl)-1,2,3-triazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate | non-polymer | 352.2 | 1 | Chemie (LJN) | |||
| 7 | G, H, K, L, M (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 8 | N, O (A, B) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A: 6 - 176 (UniProt: A0A1U7REJ8)
B: 16 - 352 (UniProt: Q29ST3)
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | - | expression tag |
| His 4 | - | expression tag |
| Met 5 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 13 | - | expression tag |
| His 14 | - | expression tag |
| Met 15 | - | expression tag |
| Cys 197 | Leu 197 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58879.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1919.5 | |
| All* | Total formula weight | 60798.9 |
