6YX5

Structure of DrrA from Legionella pneumophilia in complex with human Rab8a

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKtcV

Chain	Residue	Details
A	LEU11-VAL24

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000305|PubMed:21378754, ECO:0000305|PubMed:27552051, ECO:0007744|PDB:3QBT, ECO:0007744|PDB:5SZI

Chain	Residue	Details
A	SER17
A	LYS153
A	GLY20
A	LYS21
A	CYS23
A	GLY66
A	ASN121
A	LYS122
A	ASP124
A	ALA152

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:27552051, ECO:0007744|PDB:5SZI

Chain	Residue	Details
A	GLY18
A	VAL19
A	SER35

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:21378754, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3QBT, ECO:0007744|PDB:5SZI

Chain	Residue	Details
A	THR22
A	THR40

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:21378754, ECO:0007744|PDB:3QBT

Chain	Residue	Details
A	SER39

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site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:21378754, ECO:0007744|PDB:3QBT

Chain	Residue	Details
A	ASP63

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by LRRK2 => ECO:0000269|PubMed:26824392, ECO:0000269|PubMed:29125462, ECO:0000269|PubMed:30209220, ECO:0000269|PubMed:30398148

Chain	Residue	Details
A	THR72

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