6YWM
Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with MES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | NSP3 macrodomain | polymer | 173 | 18676.4 | 3 | UniProt (P0DTD1) Pfam (PF01661) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | pp1ab,ORF1ab polyprotein |
| 2 | D, N (A, C) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 3 | E, F, G, H, I... (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 4 | J, O (B, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | T, U, V (A, B, C) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A, B, C: 3 - 172 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| His 1 | - | expression tag |
| Met 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 56029.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1183.9 | |
| All* | Total formula weight | 57213.0 |
