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6YWM

Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with MES

Functional Information from PDB Data
site_idAC1
Number of Residues11
Detailsbinding site for residue MES A 201
ChainResidue
AALA38
AHOH347
AHOH386
AASN40
ALYS44
ASER128
AALA129
AGLY130
AILE131
APHE132
AHOH325

site_idAC2
Number of Residues6
Detailsbinding site for residue EDO A 202
ChainResidue
AGLU114
AASN115
AHOH315
AHOH346
CGLU114
CASN115

site_idAC3
Number of Residues4
Detailsbinding site for residue EDO A 203
ChainResidue
AASN117
AGLN118
AHOH306
CHOH352

site_idAC4
Number of Residues3
Detailsbinding site for residue EDO A 204
ChainResidue
AGLY79
ASER80
AASN115

site_idAC5
Number of Residues4
Detailsbinding site for residue EDO A 205
ChainResidue
AALA134
AASP135
AHIS138
BPRO74

site_idAC6
Number of Residues3
Detailsbinding site for residue EDO A 206
ChainResidue
AILE137
AARG141
BTYR42

site_idAC7
Number of Residues5
Detailsbinding site for residue MG B 201
ChainResidue
BGLY0
BHIS1
BHIS91
BHOH312
BHOH325

site_idAC8
Number of Residues7
Detailsbinding site for residue EDO B 202
ChainResidue
BALA21
BASP22
BILE23
BALA154
BVAL155
BPHE156
BHOH328

site_idAC9
Number of Residues3
Detailsbinding site for residue EDO B 203
ChainResidue
BGLY0
BHIS119
BHOH353

site_idAD1
Number of Residues3
Detailsbinding site for residue EDO B 204
ChainResidue
BGLY133
BALA134
BASP135

site_idAD2
Number of Residues10
Detailsbinding site for residue MES C 201
ChainResidue
CALA38
CASN40
CSER128
CALA129
CGLY130
CILE131
CPHE132
CHOH304
CHOH305
CHOH318

site_idAD3
Number of Residues5
Detailsbinding site for residue MG C 202
ChainResidue
AASP162
CHIS1
CASP157
CEDO203
CHOH306

site_idAD4
Number of Residues7
Detailsbinding site for residue EDO C 203
ChainResidue
AASP162
CHIS1
CMET2
CASP157
CASN159
CLEU160
CMG202

site_idAD5
Number of Residues5
Detailsbinding site for residue EDO C 204
ChainResidue
AHOH309
CASN117
CGLN118
CGLU120
CHOH326

site_idAD6
Number of Residues4
Detailsbinding site for residue EDO C 205
ChainResidue
AGLN107
ALEU108
ASER111
CARG148

site_idAD7
Number of Residues5
Detailsbinding site for residue EDO C 206
ChainResidue
CALA21
CASP22
CILE23
CALA154
CPHE156

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PDB entries from 2024-11-06

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