6YU1
CLK3 bound with beta-carboline KH-CARB13 (Cpd 3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (a, c) | Dual specificity protein kinase CLK3 | polymer | 360 | 42318.4 | 2 | UniProt (P49761) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 3 |
| 2 | AA, BA, C, CA, D... (c, a) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 22 | Chemie (EDO) | |||
| 3 | E, F, P (a, c) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 4 | EA, L (c, a) | (4~{S})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile | non-polymer | 363.2 | 2 | Chemie (KHC) | |||
| 5 | O, Q (c) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 6 | FA, GA (a, c) | water | water | 18.0 | 450 | Chemie (HOH) |
Sequence modifications
a, c: 127 - 484 (UniProt: P49761)
| PDB | External Database | Details |
|---|---|---|
| Ser 125 | - | expression tag |
| Met 126 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84636.8 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 2765.3 | |
| All* | Total formula weight | 87402.2 |
