6YTW
CLK3 bound with benzothiazole Tg003 (Cpd 2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dual specificity protein kinase CLK3 | polymer | 360 | 42318.4 | 2 | UniProt (P49761) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 3 |
| 2 | C, D, E, F, G... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) | |||
| 3 | L (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | M, O (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | N, Z (A, B) | (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one | non-polymer | 249.3 | 2 | Chemie (EAE) | |||
| 6 | Y (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | AA, BA (A, B) | water | water | 18.0 | 534 | Chemie (HOH) |
Sequence modifications
A, B: 127 - 484 (UniProt: P49761)
| PDB | External Database | Details |
|---|---|---|
| Ser 125 | - | expression tag |
| Met 126 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84636.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 1933.4 | |
| All* | Total formula weight | 86570.2 |
