Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | SER132 |
| A | SER135 |
| A | VAL145 |
| A | ASP150 |
| A | TRP151 |
| A | HOH602 |
| A | HOH607 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | GLU287 |
| A | THR337 |
| A | HIS339 |
| A | HOH630 |
| A | CYS146 |
| A | ARG147 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | ARG199 |
| A | ILE202 |
| A | ASN203 |
| A | LYS206 |
| A | TRP225 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | GLU348 |
| A | ARG402 |
| A | HOH645 |
| B | HIS330 |
| B | HIS331 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | SER323 |
| A | THR325 |
| A | THR332 |
| A | VAL335 |
| A | HOH670 |
| A | HOH731 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | ARG451 |
| A | ALA458 |
| A | GLN459 |
| A | ARG460 |
| A | GLU465 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLU454 |
| A | GLN459 |
| A | HOH779 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | ARG369 |
| A | SER433 |
| A | TYR434 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | GLU387 |
| A | PRO392 |
| A | ILE393 |
| A | GLY411 |
| A | LEU412 |
| A | ASN417 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 510 |
| Chain | Residue |
| A | LYS403 |
| A | LYS405 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 A 511 |
| Chain | Residue |
| A | ARG189 |
| A | ARG189 |
| A | LYS193 |
| A | LYS193 |
| A | TYR194 |
| A | TYR194 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EAE A 512 |
| Chain | Residue |
| A | LYS186 |
| A | PHE236 |
| A | GLU237 |
| A | LEU238 |
| A | LEU239 |
| A | GLY240 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 B 501 |
| Chain | Residue |
| B | ARG189 |
| B | ARG189 |
| B | LYS193 |
| B | LYS193 |
| B | TYR194 |
| B | TYR194 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| A | HOH770 |
| B | ARG402 |
| B | LYS403 |
| B | LYS405 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | GLU378 |
| B | LYS405 |
| B | TYR406 |
| B | HOH672 |
| B | HOH773 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | GLU137 |
| B | ASP138 |
| B | ARG341 |
| B | HOH735 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | ARG147 |
| B | PHE244 |
| B | PHE252 |
| B | GLU366 |
| B | GLY370 |
| B | PHE371 |
| B | THR372 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | PHE371 |
| B | THR372 |
| B | LEU373 |
| B | GLN375 |
| B | ASN427 |
| B | CYS428 |
| B | TYR434 |
| B | HOH679 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 507 |
| Chain | Residue |
| B | PRO392 |
| B | SER395 |
| B | HOH625 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 508 |
| Chain | Residue |
| A | HOH690 |
| A | HOH782 |
| B | ASP447 |
| A | LYS432 |
| A | VAL443 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 509 |
| Chain | Residue |
| B | GLN459 |
| B | ARG460 |
| B | GLU465 |
| B | HOH604 |
| B | HOH732 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 510 |
| Chain | Residue |
| B | GLU287 |
| B | ASN288 |
| B | LEU290 |
| B | EAE512 |
| B | HOH721 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 511 |
| Chain | Residue |
| A | THR332 |
| A | THR333 |
| A | HOH749 |
| B | HIS330 |
| B | THR333 |
| B | HOH689 |
| site_id | AE6 |
| Number of Residues | 8 |
| Details | binding site for residue EAE B 512 |
| Chain | Residue |
| B | LEU162 |
| B | ALA184 |
| B | LYS186 |
| B | PHE236 |
| B | LEU238 |
| B | LEU239 |
| B | GLY240 |
| B | EDO510 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGTFGKVVeCldhargksq.........VALK |
| Chain | Residue | Details |
| A | LEU162-LYS186 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LtHtDLKpeNILF |
| Chain | Residue | Details |
| A | LEU279-PHE291 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP283 | |
| B | ASP283 | |
| Chain | Residue | Details |
| A | LEU162 | |
| A | LYS186 | |
| B | LEU162 | |
| B | LYS186 | |
| Chain | Residue | Details |
| A | SER135 | |
| B | SER135 | |
