6YTB
GLYCOSYLATED KNOB/DUMMY-HOLE/DUMMY FC FRAGMENT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Immunoglobulin gamma-1 heavy chain | polymer | 240 | 27086.5 | 1 | UniProt (P0DOX5) Pfam (PF07654) | Homo sapiens (Human) | Immunoglobulin gamma-1 heavy chain NIE |
| 2 | B (B) | Immunoglobulin gamma-1 heavy chain | polymer | 240 | 26881.3 | 1 | UniProt (P0DOX5) Pfam (PF07654) | Homo sapiens (Human) | Immunoglobulin gamma-1 heavy chain NIE |
| 3 | C, D (C, D) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1422.3 | 2 | In PDB GlyTouCan (G61334IA) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence modifications
A: 221 - 447 (UniProt: P0DOX5)
B: 221 - 447 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Trp 366 | Thr 368 | engineered mutation |
| Glu 370 | Lys 372 | engineered mutation |
| Gly 448 | - | expression tag |
| Gly 449 | - | expression tag |
| Gly 450 | - | expression tag |
| Gly 451 | - | expression tag |
| Ser 452 | - | expression tag |
| His 453 | - | expression tag |
| His 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Lys 357 | Glu 359 | engineered mutation |
| Ser 366 | Thr 368 | engineered mutation |
| Ala 368 | Leu 370 | engineered mutation |
| Val 407 | Tyr 409 | engineered mutation |
| Gly 448 | - | expression tag |
| Gly 449 | - | expression tag |
| Gly 450 | - | expression tag |
| Gly 451 | - | expression tag |
| Ser 452 | - | expression tag |
| His 453 | - | expression tag |
| His 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53967.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2844.6 | |
| All* | Total formula weight | 56812.4 |
