6YSN
Human TRPC5 in complex with Pico145 (HC-608)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5 | polymer | 1146 | 130760.0 | 4 | UniProt (P0AEX9) UniProt (Q9UL62) Pfam (PF01547) Pfam (PF12796) Pfam (PF00023) Pfam (PF08344) Pfam (PF00520) In PDB | Escherichia coli (strain K12) | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,TrpC5,Transient receptor protein 5,hTRP5 |
2 | A, B, C, D | 7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-[3-(trifluoromethyloxy)phenoxy]purine-2,6-dione | non-polymer | 524.9 | 4 | Chemie (PJQ) |
Sequence modifications
A, B, C, D: -379 - -11 (UniProt: P0AEX9)
A, B, C, D: 1 - 765 (UniProt: Q9UL62)
PDB | External Database | Details |
---|---|---|
Met -380 | - | initiating methionine |
Leu -26 | - | insertion |
Glu -25 | - | insertion |
Val -24 | - | insertion |
Ser -10 | - | linker |
Ser -9 | - | linker |
Gly -8 | - | linker |
Leu -7 | - | linker |
Gly -6 | - | linker |
Val -5 | - | linker |
Leu -4 | - | linker |
Phe -3 | - | linker |
Gln -2 | - | linker |
Gly -1 | - | linker |
Pro 0 | - | linker |
PDB | External Database | Details |
---|---|---|
Met 455 | Val 455 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 523040.1 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 2099.5 | |
All* | Total formula weight | 525139.6 |