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6YR6

14-3-3 sigma in complex with hDM2-186 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, C, E, G)
14-3-3 protein sigmapolymer23626542.94UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B, D, F, H
(B, D, F, H)
hDM2-186polymer131626.74UniProt (by SIFTS) (Q00987)Homo sapiens
3I, J, K, L, M...
(A, C, E, G)
IODIDE IONnon-polymer126.911Chemie (IOD)
4N, U
(C, G)
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer282.32Chemie (B3P)
5AA, BA, CA, V, W...
(F, G, H, A, B...)
waterwater18.0693Chemie (HOH)
Sequence modifications
A, C, E, G: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight112678.6
Non-Polymers*Number of molecules13
Total formula weight1960.6
All*Total formula weight114639.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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