6YL4

Soluble epoxide hydrolase in complex with 3-((R)-3-(1-hydroxyureido)but-1-yn-1-yl)-N-((S)-3-phenyl-3-(4-trifluoromethoxy)phenyl)propyl)benzamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Bifunctional epoxide hydrolase 2	polymer	346	39648.5	1	UniProt (P34913) Pfam (PF00561)	Homo sapiens (Human)
2	B (A)	3-[(3~{R})-3-[aminocarbonyl(oxidanyl)amino]but-1-ynyl]-~{N}-[(3~{S})-3-phenyl-3-[4-(trifluoromethyloxy)phenyl]propyl]benzamide	non-polymer		525.5	1	Chemie (OWW)
3	C (A)	water	water		18.0	93	Chemie (HOH)

Sequence modifications

A: 222 - 555 (UniProt: P34913)

PDB	External Database	Details
Met 219	-	initiating methionine
Ala 220	-	expression tag
Ser 221	-	expression tag
Leu 556	-	expression tag
Leu 557	-	expression tag
Glu 558	-	expression tag
His 559	-	expression tag
His 560	-	expression tag
His 561	-	expression tag
His 562	-	expression tag
His 563	-	expression tag
His 564	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	39648.5
Non-Polymers*	Number of molecules	1
	Total formula weight	525.5
All*	Total formula weight	40174.1

*Water molecules are not included.