6YJP

Crystal structure of a complex between glycosylated NKp30 and its deglycosylated tumour ligand B7-H6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E (C, D, E)	Natural cytotoxicity triggering receptor 3 ligand 1	polymer	234	26286.7	3	UniProt (Q68D85) Pfam (PF07654)	Homo sapiens (Human)	B7 homolog 6,B7-H6
2	C, D (A, B)	Natural cytotoxicity triggering receptor 3	polymer	126	13917.6	2	UniProt (O14931) Pfam (PF07686)	Homo sapiens (Human)	Activating natural killer receptor p30,Natural killer cell p30-related protein,NKp30
3	F, G, H, I, J (C, D, A, B, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)

Sequence modifications

C, D, E: 24 - 244 (UniProt: Q68D85)

PDB	External Database	Details
Ile 22	-	expression tag
Thr 23	-	expression tag
Ser 212	Cys 212	engineered mutation
Gly 245	-	expression tag
Thr 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
Gly 255	-	expression tag

A, B: 19 - 130 (UniProt: O14931)

PDB	External Database	Details
Ile 16	-	expression tag
Thr 17	-	expression tag
Gly 18	-	expression tag
Gly 131	-	expression tag
Thr 132	-	expression tag
His 133	-	expression tag
His 134	-	expression tag
His 135	-	expression tag
His 136	-	expression tag
His 137	-	expression tag
His 138	-	expression tag
His 139	-	expression tag
His 140	-	expression tag
Gly 141	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	106695.3
Non-Polymers*	Number of molecules	5
	Total formula weight	1106.0
All*	Total formula weight	107801.3

*Water molecules are not included.