6YIO

CRYSTAL STRUCTURE OF FAB RG6292 IN COMPLEX WITH CD25 ECD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Interleukin-2 receptor subunit alpha	polymer	203	23219.9	1	UniProt (P01589) Pfam (PF00084)	Homo sapiens (Human)	IL2-RA,TAC antigen,p55
2	B (H)	FAB FRAGMENT HEAVY CHAIN	polymer	227	23646.6	1		Homo sapiens (Human)
3	C (L)	FAB FRGAMENT LIGHT CHAIN	polymer	214	23397.0	1		Homo sapiens (Human)
4	D, E, F (B, H, L)	water	water		18.0	589	Chemie (HOH)

Sequence modifications

B: 1 - 192 (UniProt: P01589)

PDB	External Database	Details
Ala 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70263.5
All*	Total formula weight	70263.5

*Water molecules are not included.